Moreover The Incorporation Requires The Same Components

If, For Example, All The Codons Are Triplets, Then In Addition To The Correct Reading Of The Message, There Are Two Incorrect Readings Which We Shall Obtain If We Do Not Start The Grouping Into Sets Of Three At The Right Place.

The Major Credit I Think Jim And I Deserve ... Is For Selecting The Right Problem And Sticking To It. It's True That By Blundering About We Stumbled On Gold, But The Fact Remains That We Were Looking For Gold. Both Of Us Had Decided, Quite Independently Of Each Other, That The Central Problem In Molecular Biology Was The Chemical Structure Of The Gene. ... We Could Not See What The Answer Was, But We Considered It So Important That We Were Determined To Think About It Long And Hard, From Any Relevant Point Of View.

Again The Message To Experimentalists Is: Be Sensible But Don't Be Impressed Too Much By Negative Arguments. If At All Possible, Try It And See What Turns Up. Theorists Almost Always Dislike This Sort Of Approach.

Since I Essentially Knew Nothing, I Had An Almost Completely Free Choice.

Protein Synthesis Is A Central Problem For The Whole Of Biology, And That It Is In All Probability Closely Related To Gene Action.